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KMID : 0882420150880030340
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Korean Journal of Medicine
2015 Volume.88 No. 3 p.340 ~ p.345
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A Case of Acute Osteomyelitis of the Femur Caused by Nalidixic-Acid-Resistant Salmonella enteritidis
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Na Seong-Kyun
Kim Tae-Jun
Lee Jeong-A
Lee Seung-Soon
Koh Sung-Hye
Kim Tae-Young
Kim Han-Sung
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Abstract
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Infection with nontyphoidal Salmonella most often results in self-limited acute gastroenteritis. However, occasionally it causes bacteremia and localized infection requiring antibiotic treatment. A third-generation cephalosporin or fluoroquinolone is often the first choice of antibiotic. However, there has been an increase in nalidixic-acid-resistant nontyphoidal Salmonella with decreased fluoroquinolone susceptibility. Although there have been many cases reported of nontyphoidal Salmonella, no cases of nalidixic-acid-resistant nontyphoidal Salmonella have been reported in Korea. Here, we report on the case of a 61-year-old man with a diagnosis of acute osteomyelitis and periosteal abscess of the femur caused by nalidixic-acid-resistant Salmonella enteritidis. He was treated successfully with prolonged administration of a high-dose of ciprofloxacin and drainage of the abscess.
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KEYWORD
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Salmonella enteritidis, Osteomyelitis, Nalidixic acid, Drug resistance
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